A REVIEW ON CHALLENGES IN DEVELOPING NASAL SPRAYS

The aim of this review is to provide information regarding significant aspects and challenges in developing nasal sprays. This article outlined the relevant anatomy, physiology & biological, physicochemical pharmaceutical factors that must be considered during formulation development Nasal drug delivery system most preferable route than other routes administration as it gives rapid onset action. It a convenient reliable for local also systemic drugs. main highlights includes types, advantages, disadvantages, mechanisms absorption, formulation, methods manufacturing filling sprays, evaluation, characterization applications.